KHAN YOUNIS, Gaza Strip (AP) — A massive blast rocked a Gaza City hospital packed with wounded and other Palestinians seeking shelter Tuesday, killing hundreds of people, the Hamas-run Health Ministry said. Hamas blamed an Israeli airstrike, while the Israeli military said the hospital was hit by a rocket misfired by Palestinian militants. The Gaza Health Ministry said at least 500 people were killed.

As rage spread through the region because of the hospital carnage, and with President Joe Biden heading to the Mideast in hopes of stopping the war from spreading, Jordan’s foreign minister said his country canceled a regional summit scheduled for Wednesday in Amman, where Biden was to meet with Jordan’s King Abdullah II, Palestinian President Mahmoud Abbas and Egyptian President Abdel Fattah el-Sissi.

The war between Israel and Hamas was “pushing the region to the brink,” Foreign Minister Ayman Safadi told state-run television. He said Jordan would host the summit only when everyone had agreed its purpose would be to “stop the war, respect the humanity of the Palestinians and deliver the aid they deserve.”